Table 2.
NMI-LG | NMI-HG | MI-HG | NED | Control | p-Value | |||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Center 1 | Center 2 | Center 1 | Center 2 | Center 1 | Center 2 | Center 1 | Center 2 | Center 1 | Center 2 | Center 1 | Center 2 | |
n | 78 | 56 | 26 | 22 | 25 | 35 | 30 | 32 | 78 | 148 | ||
Age Mean (SD) Median Range |
71.1 (11.6) 74 33–90 |
70.8 (12.4) 72 26–92 |
74.9 (11.6) 78.5 52–94 |
72.5 (9.4) 75 51–92 |
74.2 (11.0) 75 52–98 |
73.2 (9.3) 74 53–88 |
73.0 (8.8) 73.5 46–88 |
68.8 (13.1) 70.5 46–88 |
67.6 (12.64) 69.5 31–86 |
69.6 (11.94) 71.5 33–93 |
0.042 | 0.554 |
Gender Female (%) Male (%) |
20 (25.6) 58 (74.4) |
14 (25.0) 42 (75.0) |
4 (15.4) 22 (84.6) |
2 (9.1) 20 (90.9) |
6 (24.0) 19 (76.0) |
13 (37.1) 22 (62.9) |
3 (10.0) 27 (90.0) |
7 (21.9) 25 (78) |
23 (29.5) 55 (70.5) |
47 (31.8) 101 (68.2) |
0.220 | 0.127 |
Diabetes | 22 (28.2%) | 3 (5.4%) | 6 (23.1) | 2 (9.1%) | 6 (24%) | 6 (17.1%) | 5 (16.7%) | 5 (15.6%) | 13 (16.7%) | 21 (14.2%) | 0.469 | 0.337 |
Erythrocyte pos. | 45 (57.7%) | 38 (67.9%) | 24 (92.3%) | 20 (91.0%) | 24 (96.0%) | 34 (97.1%) | 17 (56.7%) | 21 (65.6%) | 34 (43.6%) | 39 (26.4%) | <0.001 | <0.001 |
Leucocytes Mean (SD) Median Range |
79.17 (165.2) 0 0–500 |
92.39 (183.8) 0 0–500 |
142.3 (182.04) 100 0–500 |
71.6 (143.4) 25 0–500 |
249.0 (229.41) 100 0–500 |
215.4 (229.5) 100 0–500 |
142.50 (220.1) 25 0–500 |
113.55 (195.2) 0 0–500 |
76.6 (165.60) 0 0–500 |
57.7 (141.68) 0 0–500 |
<0.001 | <0.001 |
Nitrite pos. | 3 (3.8%) | 2 (3.6%) | 4 (5.1%) | 1 (1.8%) | 2 (8%) | 6 (17.1%) | 1 (3.3%) | 2 (6.3%) | 3 (3.8%) | 9 (6.1%) | 0.199 | 0.185 |
Cystoscopy | 47 (60.3%) | 53 (94.6%) | 11 (42.3%) | 22 (100%) | 11 (44%) | 31 (88.6%) | 20 (66.7%) | 29 (90.6%) | 16 (20.5%) | 20 (13.5%) | <0.001 | <0.001 |
UBC [µg/L] Mean (SD) Median Range |
21.1 (43.7) 6.5 5–300 |
44.6 (81.9) 6.2 5–300 |
83.9 (94.8) 41.4 5–300 |
109.3 (115.8) 59.4 5–300 |
61.4 (80.9) 28.9 5–300 |
70.9 (97.1) 20.7 5–300 |
7.48 (7.06) 5 5–39.1 |
12.37 (11.4) 6.5 5–56.5 |
7.8 (13.9) 5 5–121 |
7.6 (14.0) 5 5–166 |
<0.001 | <0.001 |
Sensitivity Specificity PPV NPV |
38.5% 92.3% 83.3% 60.0% |
39.3% 94.6% 73.3% 80.5% |
73.1% 92.3% 76.0% 91.1% |
77.3% 94.6% 68.0% 96.6% |
68.0% 92.3% 73.9% 90.0% |
68.6% 94.6% 75.0% 92.7% |
6.7% 92.3% 25% 72% |
37.5% 94.6% 60% 87.5% |