Table 1.
Genes Upregulated in Liver and Downregulated in Kidney during Spaceflight.
| Gene Set | Kidney Gene # | Liver Gene # | Kidney ES | Liver ES | Kidney NES | Liver NES | Kidney FWERp | Liver FWERp | Kidney Np | Liver Np | Kidney FDRq | Liver FDRq | Kidney Rank | Liver Rank |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| T cell activation | 29 | 29 | −0.26 | 0.19 | −1.37 | 0.67 | 0.338 | 1 | 0 | 0.933 | 0.186 | 1 | 6874 | 6586 |
| Positive regulation of T cell activation | 18 | 18 | −0.26 | 0.29 | −1.09 | 0.94 | 0.882 | 1 | 0.281 | 0.559 | 0.393 | 0.972 | 6874 | 4085 |
| Regulation of Lymphocyte activation | 26 | 26 | −0.26 | 0.21 | −1.44 | 0.75 | 0.208 | 1 | 0 | 0.869 | 0.163 | 1 | 6874 | 6695 |
| Positive regulation of Lymphocyte activation | 20 | 20 | −0.26 | 0.22 | −1.25 | 0.74 | 0.574 | 1 | 0.091 | 0.854 | 0.19 | 1 | 6874 | 4085 |
| Regulation of T cell activation | 21 | 21 | −0.26 | 0.24 | −1.26 | 0.8 | 0.535 | 1 | 0.071 | 0.786 | 0.206 | 0.997 | 6874 | 4085 |
| Calcium channel activity | 20 | 20 | −0.27 | 0.22 | −1.36 | 0.73 | 0.341 | 1 | 0.111 | 0.857 | 0.141 | 1 | 5840 | 2858 |
| Extracellular matrix structural constituent | 15 | 15 | −0.24 | 0.35 | −1.03 | 1.09 | 0.946 | 1 | 0.526 | 0.343 | 0.453 | 0.873 | 6985 | 4443 |
| Heart development | 24 | 24 | −0.3 | 0.23 | −1.49 | 0.78 | 0.173 | 1 | 0 | 0.828 | 0.272 | 1 | 6497 | 4327 |
| Hormone metabolic process | 16 | 16 | −0.16 | 0.35 | −0.65 | 1.1 | 0.999 | 1 | 0.919 | 0.336 | 0.97 | 0.835 | 7751 | 4932 |
Gene # is the number of genes in the pool. ES is the enrichment score. NES is the normalized enrichment score. FWERp is the Family Wise Error Rate p-value. Np is the Normalized p-value. FDRq is the False Discovery Rate q-value. Rank is the Rank at Maximum.