Table 2.
Genes Upregulated in Kidney and Downregulated in Liver during Spaceflight.
| Gene Set | Kidney Gene # | Liver Gene # | Kidney ES | Liver ES | Kidney NES | Liver NES | Kidney FWERp | Liver FWERp | Kidney Np | Liver Np | Kidney FDRq | Liver FDRq | Kidney Rank | Liver Rank |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Amine receptor activity | 23 | 23 | 0.24 | −0.21 | 0.79 | −1.01 | 1 | 0.983 | 0.8 | 0.55 | 1 | 0.964 | 2860 | 7304 |
| Amino acid catabolic process | 19 | 19 | 0.22 | −0.17 | 0.68 | −0.79 | 1 | 1 | 0.917 | 0.964 | 1 | 0.836 | 3122 | 6652 |
| Blood coagulation | 35 | 35 | 0.24 | −0.19 | 0.82 | −1.1 | 1 | 0.94 | 0.81 | 0.4 | 1 | 0.833 | 6444 | 6951 |
| Coagulation | 35 | 35 | 0.24 | −0.19 | 0.82 | −0.98 | 1 | 0.991 | 0.79 | 0.75 | 1 | 0.684 | 6444 | 6951 |
| Cell division | 18 | 18 | 0.19 | −0.33 | 0.59 | −1.3 | 1 | 0.548 | 0.968 | 0.158 | 0.998 | 0.326 | 4143 | 6233 |
| DNA packaging | 23 | 23 | 0.3 | −0.21 | 0.97 | −0.98 | 1 | 0.991 | 0.532 | 0.577 | 1 | 0.782 | 5378 | 7345 |
| Cytokinesis | 16 | 16 | 0.2 | −0.34 | 0.6 | −1.46 | 1 | 0.229 | 0.964 | 0.02 | 1 | 0.159 | 448 | 6088 |
| ER Golgi intermediate compartment |
16 | 16 | 0.35 | −0.22 | 1.06 | −0.94 | 1 | 0.994 | 0.39 | 0.566 | 0.923 | 0.712 | 5924 | 7226 |
| Neuropeptide binding | 17 | 17 | 0.29 | −0.2 | 0.89 | −0.93 | 1 | 0.994 | 0.67 | 0.679 | 1 | 0.648 | 4808 | 6250 |
| Neuropeptide receptor Activity |
17 | 17 | 0.29 | −0.2 | 0.89 | −0.77 | 1 | 1 | 0.638 | 0.853 | 1 | 0.792 | 4808 | 6250 |
| Peptide receptor activity | 38 | 38 | 0.29 | −0.15 | 1.01 | −1 | 1 | 0.988 | 0.477 | 0.5 | 0.99 | 0.84 | 4920 | 6917 |
| Rhodopsin like receptor activity | 80 | 80 | 0.23 | −0.15 | 0.86 | 1 | 0 | 0.834 | 1 | 1 | 5403 | 7907 |
Gene # is the number of genes in the pool. ES is the enrichment score. NES is the normalized enrichment score. FWERp is the Family Wise Error Rate p-value. Np is the Normalized p-value. FDR q is the False Discovery Rate q-value. Rank is the Rank at Maximum.