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. 2018 Dec 6;19(12):3903. doi: 10.3390/ijms19123903

Figure 3.

Figure 3

Intracellular accumulation of Berberine enhanced by Res in Hepatic L02 cells. (A,B) intracellular fluorescence of Ber in a dose-dependent manner (0–100 µmol/L), and mean fluorescence intensity (MFI) calculated and compared in different dose of Ber groups. *** p < 0.001, ** p < 0.01, * p < 0.05 vs. untreated control. (C,D) Res at 10 or 25 µmol/L added in advance (details indicated in Material and Methods) enhanced intracellular fluorescence of Ber at 50 µmol/L, MFI calculated and compared, *** p < 0.001 vs. untreated control, # p < 0.05 vs. single Ber treatment. Data shown are representative of three separate assays.