Table 2.
Parameter | pIC50 | ClogP | MR | µ | µe |
---|---|---|---|---|---|
pIC50 | 1.000 | 0.850 | 0.726 | 0.427 | 0.647 |
ClogP | 0.850 | 1.000 | 0.606 | 0.352 | 0.597 |
MR | 0.726 | 0.606 | 1.000 | 0.301 | 0.217 |
µ | 0.427 | 0.352 | 0.301 | 1.000 | −0.035 |
µe | 0.647 | 0.597 | 0.217 | −0.035 | 1.000 |
pIC50 = log(106/IC50); CLoP: Partition coefficient; MR: molar refractivity, µ: dipolar momentum; µe: Electronic potential.