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. 2018 Dec 4;19(12):3881. doi: 10.3390/ijms19123881

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© 2018 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Weighted gene correlation network analysis (WGCNA) and pathway analysis using RNA-sequencing (RNA-seq) data from the TCGA stomach cancer dataset. (A) WGCNA cluster dendrogram of differentially expressed mRNAs and lncRNAs. Each leaf (vertical line) in the dendrogram corresponds to a gene. The color row underneath the dendrogram shows the assigned original module and the merged module. The lncRNA candidates PCAT18 and LINC01133 were clustered in the red module; (B) The lncRNA-mRNA network of the red module visualized using the cytoscape software platform; (C) Over-represented terms in the Molecular and Cellular Function category; (D) Top diseases and biofunctions related to co-expressed genes.