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. 2018 Dec 8;19(12):3950. doi: 10.3390/ijms19123950

Figure 5.

Figure 5

BH3-mimicking and apoptosis induction BH-3-mimicking peptides bind to anti-apoptotic Bcl-2-like proteins as competitive inhibitors, allowing BH-3-activators release and pro-apoptotic Bax/Bak-like proteins activation leading to cell death.