An official website of the United States government
Here's how you know
Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
BH3-mimicking and apoptosis induction BH-3-mimicking peptides bind to anti-apoptotic Bcl-2-like proteins as competitive inhibitors, allowing BH-3-activators release and pro-apoptotic Bax/Bak-like proteins activation leading to cell death.