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. 2018 Dec 18;19(12):4105. doi: 10.3390/ijms19124105

Figure 2.

Figure 2

Increased expression of macrophage migration inhibitory factor (MIF), CXCR4, and CD74 in lungs from bleomycin (BLM)-injected mice. (A) Representative images of MIF (red; upper panel), CXCR4 (red; middle panel), and CD74 (red; lower panel) staining with α-smooth muscle actin (α-SMA; green) and DAPI (blue) in lungs from control and BLM-injected mice. (B) Representative Western blots and quantification of the CXCR4/GAPDH and CD74/GAPDH ratios in lungs from control and BLM-injected mice. (C) Levels of circulating MIF proteins in the serum of BLM-injected mice compared to those of control mice. Values are means ± SEM (n = 4–8), where n represents the number of mice. * p < 0.05; ** p < 0.01 compared to control mice. Scale bar = 20 μm in all sections. AU = arbitrary unit; DAPI = 4′,6-diamidino-2-phenylindole.