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. 2018 Dec 18;19(12):4105. doi: 10.3390/ijms19124105

Figure 3.

Figure 3

Chronic treatment with ISO-1 and compound 31 attenuates matrix deposition in lungs from bleomycin (BLM)-injected mice. (A) Representative images of hematoxylin eosin (H&E), Picrosirius red, or Masson’s trichrome staining and analysis of second harmonic generation (SHG) of radiations with a fundamental wavelength of 800 nm, and (B) quantification of the SHG score in lungs from control and BLM-injected mice. Values are means ± SEM (n = 4–8), where n represents the number of mice. **** p < 0.001 compared to control mice; ### p < 0.001 and #### p < 0.0001 compared to BLM-injected mice. Scale bar = 50 μm in all sections.