Table 2.

Permeated amount of β-arbutin after 24 h, deposited on the skin, and penetrated across the skin. Data are mean ± SD values. C, penetrating β-arbutin alone; L, laser combined with penetrating β-arbutin; L + S, laser combined with saline and penetrating β-arbutin; L + MBs, laser combined with MBs and penetrating β-arbutin.

Group	Skin Weight (mg)	Amount of β-arbutin Penetrated Across Skin (mg/mL)	Amount of β-arbutin Deposited on Skin (mg/mL)	Total Amount of β-arbutin Penetrated (mg/mL)
C	18.88 ± 3.30	2.397 ± 0.07	2.291 ± 0.419	4.688 ± 0.491
L	23.43 ± 0.93	4.876 ± 0.017	2.559 ± 0.129	7.435 ± 0.146
L + S	18.75 ± 3.54	3.287 ± 0.01	3.355 ± 0.350	6.642 ± 0.451
L + MBs	22.47 ± 1.10	4.892 ± 1.14	3.292 ± 0.481	8.184 ± 1.628