Table 3.
Multivariate regression analysis for knee OA at 2-year and/or 5-year follow up according to the ACR classification criteria (n = 64, 35 cases, a priori risk = 0.55)
| Baseline characteristics | Analysis per category OR (95% CI) | Multivariate analysis OR (95% CI) | PPV | NPV | LR+ | LR- |
|---|---|---|---|---|---|---|
| Demographics | ||||||
| Age (<=50 vs. > 50 years) | 0.37 (0.13–1.36) | 0.42 (0.14–1.06) | 0.39 | 0.37 | 0.53 | 1.44 |
| Complaints and symptoms | ||||||
| Morning stiffness knee (yes = 1/no = 0) | 6.79 (0.65–51.23) | 6.08 (0.53–69.93) | 0.86 | 0.49 | 4.97 | 0.08 |
| Physical examination | ||||||
| Joint line tenderness | 1.05 (0.21–5.14) | 1.92 (0.34–10.79) | 0.73 | 0.5 | 2.2 | 0.8 |
| Diagnostic tests | ||||||
| ESR < 20 mm/h | 0.94 (0.87–1.02) | 0.94 (0.85–1.03) | na | na | na | na |
OR odds ratio, PPV positive predictive value, NPV negative predictive value, NRS numeric rating scale, ESR erythrocyte sedimentation rate, LR+ positive likelihood ratio, LR- negative likelihood ratio, na not applicable (continuous variable)
p < 0.05