Table 3.
Percent Difference in Fibroid Size and Uterine Volume Associated with Specific Gravity-Adjusted Phthalate Biomarker Concentrations.
| Percent difference (95% CI)a | ||||
|---|---|---|---|---|
| Fibroid size (cm) | Uterine volume (cm3) | |||
| Unadjusted | Adjustedb | Unadjusted | Adjustedb | |
| N = 57 | N = 57 | N = 56 | N = 56 | |
| Phthalate biomarkers (ng/mL) | ||||
| MEP | 3.5 (−2.1, 9.4) | 0.4 (−5.8, 7.0) | 8.0 (−2.0, 19.1) | 6.7 (−5.0, 19.7) |
| MnBP | −0.8 (−11.9, 11.7) | −2.6 (−13.2, 9.4) | 7.6 (−12.9, 32.8) | 10.4 (−10.3, 35.9) |
| MHBP | −3.7 (−18.4, 13.6) | 1.1 (−14.0, 18.9) | 7.7 (−19.7, 44.4) | 25.7 (−5.7, 67.5) |
| MiBP | 2.8 (−10.2, 17.7) | 2.7 (−10.7, 18.0) | 3.0 (−19.0, 30.9) | 8.3 (−15.7, 39.0) |
| MHiBP | 6.0 (−8.2, 22.5) | 9.5 (−5.2, 26.6) | 7.9 (−16.5, 39.4) | 22.7 (−5.2, 58.9) |
| MBzP | 1.1 (−8.5, 11.7) | 0.7 (−8.5, 10.9) | 10.4 (−7.4, 31.5) | 11.8 (−5.8, 32.7) |
| MCPP | 4.2 (−4.2, 13.4) | 3.5 (−4.5, 12.0) | 9.1 (−5.9, 26.5) | 9.8 (−4.8, 26.5) |
| MCOP | 4.3 (−2.6, 11.6) | 4.2 (−2.3, 11.1) | 6.3 (−5.8, 20.0) | 8.2 (−3.6, 21.6) |
| MCNP | 4.1 (−6.2, 15.5) | 4.3 (−5.4, 15.0) | 13.9 (−5.0, 36.5) | 15.5 (−2.8, 37.2) |
| MEHP | 3.4 (−9.5, 18.0) | 4.7 (−7.4, 18.5) | 14.9 (−9.3, 45.7) | 18.1 (−5.6, 47.7) |
| MEHHP | 6.5 (−5.9, 20.5) | 2.8 (−8.7, 15.6) | 31.5 (6.8, 61.9)c | 26.2 (3.1, 54.6)c |
| MEOHP | 5.0 (−6.9, 18.3) | 1.5 (−9.4, 13.7) | 31.8 (8.0, 60.9)c | 27.1 (4.7, 54.3)c |
| MECPP | 9.9 (−3.7, 25.4) | 6.3 (−6.3, 20.5) | 36.6 (9.1, 71.1)c | 31.6 (5.9, 63.5)c |
| ΣDEHP | 8.6 (−5.3, 24.6) | 4.8 (−8.0, 19.4) | 39.3 (10.7, 75.3)c | 33.2 (6.6, 66.4)c |
| ΣAA Phthalates | 10.0 (−3.0, 24.7) | 5.0 (−7.3, 18.9) | 30.3 (4.9, 61.9)c | 26.8 (2.2, 57.4)c |
Abbreviations: CI, confidence interval
a
Percent difference is for a doubling of phthalate biomarker concentration (ng/mL).
b
Adjusted for age (continuous), BMI (continuous), and race/ethnicity (Black vs. White or Latina).
c
P < 0.05