Table 3.
Variablea | Raw MMSE Scoresb | |||||||
---|---|---|---|---|---|---|---|---|
Model 1 | Model 2 | Model 3 | Model 4 | |||||
95% CI | 95% CI | 95% CI | 95% CI | |||||
2004–2005 cohort overall | −1.53 | −1.94, −1.22 | −1.94 | −2.33, −1.54 | −2.07 | −2.48, −1.67 | −2.03 | −2.41, 1.66 |
Time | −1.02 | −1.10, −0.94 | −1.00 | −1.10, −0.90 | −0.98 | −1.08, −0.87 | −0.87 | −1.00, 0.75 |
Cohort × time | 0.53 | 0.43, 0.63 | 0.52 | 0.41, 0.62 | 0.50 | 0.39, 0.62 | 0.58 | 0.48, 0.67 |
Age | −0.33 | −0.37, −0.29 | −0.29 | −0.33, −0.25 | −0.29 | −0.33, −0.25 | −0.26 | −0.30, −0.22 |
Female sex | −0.20 | −0.57, 0.17 | −0.17 | −0.53, 0.18 | −0.003 | −0.37, 0.36 | −0.05 | −0.42, 0.32 |
US born | 0.84 | 0.47, 1.21 | −0.14 | −0.51, 0.22 | −0.14 | −0.51, 0.22 | −0.20 | −0.58, 0.18 |
Education | 0.49 | 0.41, 0.62 | 0.47 | 0.42, 0.52 | 0.47 | 0.42, 0.52 | ||
Diabetes | −0.07 | −0.47, 0.32 | −0.20 | −0.61, 0.22 | ||||
Heart disease | 0.51 | −0.06, 1.08 | 0.64 | 0.08, 1.20 | ||||
Hypertension | 0.32 | −0.06, 0.69 | 0.32 | −0.07, 0.71 | ||||
Stroke | −2.10 | −2.79, −1.41 | −1.92 | −2.62, −1.22 | ||||
Depression | −1.74 | −2.19, −1.29 | −1.62 | −2.08, −1.16 | ||||
Covariate × time | ||||||||
Age | −0.08 | −0.09, −0.07 | ||||||
Female sex | −0.04 | −0.13, 0.05 | ||||||
US born | 0.04 | −0.06, 0.13 | ||||||
Education | −0.02 | −0.03, −0.01 | ||||||
Diabetes | −0.11 | −0.22, 0.001 | ||||||
Heart disease | −0.06 | −0.21, 0.09 | ||||||
Hypertension | −0.07 | −0.16, 0.03 | ||||||
Stroke | −0.03 | −0.26, 0.19 | ||||||
Depression | −0.19 | −0.31, 0.07 |
Abbreviations: CI, confidence interval; MMSE, Mini-Mental State Examination.
a The coefficient for the practice effect term is suppressed from the table.
b Results are from joint longitudinal-survival models. Model 1 controlled for age, sex, and nativity. Model 2 controlled for covariates in model 1 plus education. Model 3 controlled for covariates in model 2 plus diabetes, heart disease, hypertension, stroke, and depression. Model 4 controlled for covariates in model 3 plus interaction terms between time and all covariates.