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Growth of WT and individual mutant viruses in the presence of F10 or oseltamivir. (A) WT and mutant viruses (HA, NA, and HA-NA double mutant) were grown in the indicated concentrations of F10 and quantified by plaque assay. (B) Viral response to the NA inhibitor oseltamivir was measured for the resistance mutation H275YNA compared to responses of the wild type and the mutation E329KNA. Error bars in panel A indicate the standard deviations.
