Table 2.

Adjusted association of prehospital care with door-to-antibiotic time in community-dwelling patients with sepsis

Comparison	Adjusted Difference in Door-to-Antibiotic Time* (95% CI)	P Value
Overall comparison		0.021†
Basic life support vs. no prehospital care, min	−3.9 (−41.7 to 33.9)	0.98‡
Advanced life support vs. no prehospital care, min	−43.1 (−93.5 to −2.8)	0.033‡
Advanced life support vs. basic life support, min	−39.2 (−77.8 to −0.6)	0.046‡

Definition of abbreviation: CI = confidence interval.

^*Adjusted for nighttime emergency department arrival, Mortality in Emergency Department Sepsis score, source of infection, Hispanic ethnicity or nonwhite race, age, Charlson Comorbidity Index, first-available Glasgow Coma Score, first-available systolic blood pressure, and first-available respiratory rate.

^†Result of F test to assess overall significant effect of prehospital level of care on door-to-antibiotic time.

^‡Confidence intervals and P values adjusted for multiple comparisons using Tukey multiple comparisons correction.