Table 1.

Summary of patients with corneal stromal invasion of conjunctival squamous cell carcinoma

Patient	Age, years	Sex	Race	Geographic location	Location of lesion	Initial surgery and pathology	Interval to corneal opacity, months	Initial management of corneal invasion	Final surgery	Final pathology	Follow-up, years	Local recurrence/metastasis after final surgery
1	47	F	Caucasian	Australia	Nasal limbus	Simple excision; conjunctival intraepithelial neoplasia, grade 1	18	Topical interferon and retinoic acid, FML, lamellar keratoplasty for recurrence	Enucleation	SCC with deep corneal stromal, forniceal, and scleral invasion	5	None
2	61	M	Caucasian	Australia	Nasal limbus	Simple excision; pterygium with focal low-grade dysplasia	12	Oral doxycycline, topical FML, topical interferon	Enucleation	Mucoepidermoid carcinoma with deep corneal stromal, scleral and intraocular invasion	6	None
3	65	M	Caucasian	USA	Temporal limbus	Simple excision; mucoepidermoid carcinoma	24	Lamellar keratoplasty, plaque brachytherapy	N/A	Mucoepidermoid carcinoma with deep corneal stromal invasion	7	None
4	75	M	Caucasian	USA	Temporal limbus	Simple excision; not submitted for pathologic evaluation	12	Resection of limbal mass, deep tenonectomy, resection of lateral rectus, eccentric penetrating keratoplasty	Enucleation	SCC with extensive deep corneal stromal invasion	2	None

F, female; M, male; FML, fluorometholone; SCC, squamous cell carcinoma; N/A, not applicable.