Table 3.
Association of severity of LA enlargement and all-cause mortality
| Variable | Model 1 | Model 2 | Model 3 | |||
|---|---|---|---|---|---|---|
| Hazards ratio (95% CI) | P - value | Hazards ratio (95% CI) | P - value | Hazards ratio (95% CI) | P - value | |
| Normal LA size | 1.00 | – | 1.00 | 1.00 | – | |
| Mild LA enlargement | 1.35 (1.11, 1.65) | 0.003 | 1.27 (1.04, 1.55) | 0.022 | 1.04 (0.78, 1.36) | 0.76 |
| Moderate LA enlargement | 1.51 (1.22, 1.88) | < 0.001 | 1.32 (1.05, 1.66) | 0.017 | 1.45 (1.1, 1.89) | 0.006 |
| Severe LA enlargement | 2.14 (1.81, 2.53) | < 0.001 | 1.9 (1.58, 2.28) | < 0.001 | 1.64 (1.29, 2.08) | < 0.001 |
| LAVI (for every 5 ml increase) | 1.01 (1.002, 1.01) | < 0.001 | 1.004 (1.002, 1.01) | 0.001 | 1.004 (1, 1.01) | 0.046 |
Model 1 – Univariate analysis
Model 2 – Adjusted for clinical variables; age, gender, atrial fibrillation, history of hypertension, history of diabetes and history of myocardial infarction
Model 3 – Model 2 + adjusted for CMR variables; left ventricular ejection fraction, left ventricular mass, left ventricular scar, right ventricular ejection fraction