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. 2019 Jan 7;25:1. doi: 10.1186/s10020-018-0068-8

Table 3.

Histology score adapted from Read et al. (2001)

Score 0 1 2 3 4
Mono- and polymorphonuclear infiltrate Normal Increase in mucosa Increase in mucosa and submucosa Extending into mucosa, submucosa, tunica muscularis and/or serosa
Goblet cells Normal, large amount Depletion of < 10% Depletion of 10–50% Depletion of > 50%
Crypt loss No crypt loss < 10% crypt loss 10–50% crypt loss > 50% crypt loss
Epithelial hyperplasia Normal Slight hyperplasia 2-3x increase of crypt length >3x increase of crypt length
Ulcerations No ulceration Ulcerations
Crypt abscesses No abscesses Crypt abscesses