Fig. 3.
miR-632 negatively regulates TFF1 expression in GC cells. a miRNA mimic upregulated miR-632 expression compared with the negative control in AGS and BGC823 cells. b miRNA inhibitor downregulated miR-632 expression compared with the negative control in MKN45 and MGC803 cells. c miR-632-mimic reduced TFF1 expression (left panel) and secretion (right panel) in AGS and BGC823 cells compared with the negative control. d miR-632-inhibitor increased TFF1 expression (left panel) and secretion (right panel) compared with the negative control in MGC803 and MKN45 cells. e Western blot analysis of miR-632-mimic or inhibitor treatment in GC cells. The experiments were performed at least three times independently. *P < 0.05; **P < 0.01