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. 2019 Jan 6;21:5. doi: 10.1186/s13075-018-1770-1

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — Altered response of fibroblast-like synoviocytes (FLS) lacking Bma1^−/− to inflammatory stimuli. FLS were cultured from Col6a1-Bmal1^−/− and wild-type littermates to passage 3 and purified for CD90.2 expression before stimulation for 8 h with tumour necrosis factor (TNF)-α. Expression of inflammatory cytokines in cell supernatants was assessed by Bioplex and enzyme-linked immunosorbent assay (CXCL5 only) (n = 5–6). One-way analysis of variance and post hoc Bonferroni correction. Stars directly above TNF-α bars indicate significant difference compared with control counterparts