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. 2018 Oct 1;74(1):96–107. doi: 10.1093/jac/dky386

Table 2.

MIC values of LS-sarcotoxin against a panel of Gram-negative clinical isolates

Species and resistance phenotypea (number of isolates) MIC of LS-sarcotoxin (mg/L)b
MIC50/90 (mg/L) 2 4 8 16 32 64 128 >128
E. coli (26) 4/8 22 4
 CSTR MEMR (1) 1
 CSTR (9) 8 1
 MEMR (4) 3 1
 S (12) 10 2
E. cloacae (23) 8/8 1 9 12 1
 CSTR MEMR (1)   1
 CSTR (3) 1 2
 MEMR (10)   4 5 1
 S (9)   5 4  
Enterobacter aerogenes (1) 1
 CSTR MEMR (1) 1
K. pneumoniae (21) 4/8 12 8 1
 CSTR MEMR (6) 4 2
 CSTR (9) 4 4 1
 MEMR (2) 2
 S (4) 2 2
Klebsiella oxytoca (2) 2
 MEMR (2) 2
S. enterica (10) 4/8 5 5
 CSTR (2) 1 1
 S (8) 4 4
C. freundii (1) 1
 MEMR (1) 1
A. baumannii (20) 4/8 15 5
 CSTR MEMR (3) 2 1
 MEMR (16) 12 4
 S (1) 1
Acinetobacter pittii (1) 1
 S (1) 1
P. aeruginosa (2) 2
 MEMR (2) 2
S. maltophilia (2) 1 1
 CSTR MEMR (2) 1 1
M. morganii (4) 4
 CSTR MEMR (1) 1
 CSTR (3) 3
S. fonticola (1) 1
 CSTR MEMR (1) 1
a

CSTR, resistant to colistin; MEMR, resistant to meropenem; S, susceptible to colistin and meropenem.

b

The numbers of isolates for which the MIC value was determined are tabulated.