Fig. 3.

Time-response study of cellular and biochemical parameters in BALF. Mice were intratracheally instilled with 50 µg per mouse of Nano-Ni. Control mice were instilled with physiological saline. BALF was collected from mice at days 1, 3, 7, 14, 28, and 42 post-exposure. The neutrophil count (a), CXCL1/KC level (b), LDH activity (c), and total protein concentration (d) in the BALF were determined. Data are shown as mean ± SE (n = 4 ~ 10). *p < 0.05 vs. Control