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. 2019 Jan 7;19:23. doi: 10.1186/s12879-018-3619-2

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Histopathological lesions of Crohn’s disease, a Granulomatous ileitis: granuloma formation in the mucosa (arrow). b Mixed granulomatous enteritis is seen with Infiltration of lymphocytes and plasma cells in the mucosa. c Chronic lymphoplasmacytic enteritis: Infiltration of lymphocytes and plasma cells in the mucosa. d Epithelial patchy necrosis or ulceration of mucosal of ileum (arrow). e Pyloric gland metaplasia: compound acinar glands lined by antral type mucosa of stomach are observed in the lamina propria (arrow). f Paneth cell hyperplasia: These cells with numerous cytoplasmic granules are situated at the base of crypts of Liberkuhen glands (arrow) .H & E, ileum, human