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. 2019 Jan 7;19:23. doi: 10.1186/s12879-018-3619-2

Fig. 2.

Fig. 2

Histopathological lesions of Johne’s disease, a and b Granulomatous ileitis. Infiltration of epithelioid macrophages are seen in the mucosa. c Mixed granulomatous ileitis: Infiltration of epithelioid macrophages, lymphocytes and plasma cells in the mucosa and submucosa of ileum. d Lymphoplasmacytic enteritis. Diffuse infiltration of lymphocytes and plasma cells in the mucosa and submucosa. e Lymphangiectasia. Lymphatic dilation in the mucosa and submucosa. f Lymphangitis (starisk) and lymphocytic neuritis (arrow). H & E, ileum, goat