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. 2019 Jan 7;19:17. doi: 10.1186/s12885-018-5224-6

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Kaplan-Meier estimates for OS in the axitinib- and placebo-titration arms. Modified from Rini et al. [3], Overall survival analysis from a randomized phase II study of axitinib with or without dose titration in first-line metastatic renal cell carcinoma, p 500, copyright 2016, with permission from Elsevier. Abbreviations: CI confidence interval, LLN lower limit of normal, mOS median overall survival, NE not estimable, OS overall survival