Table 4.

Reasons for treatment discontinuation of patients with OS ≥24 versus < 24 months in the axitinib titration arm

Reason for treatment discontinuation, n (%)	OS ≥24 months n = 33a	OS < 24 months n = 20b
Objective progression or relapse	17 (52)	16 (80)
Adverse event	5 (15)	2 (10)
Death	1 (3)	1 (5)
Global deterioration of health status	0	1 (5)
Patient refusal to continue treatment for reason other than adverse event	1 (3)	0
Total	24 (73)	20 (100)

Abbreviation: OS overall survival

^aIncluding 9 patients still on treatment

^bExcluded 3 patients who were censored < 24 months in OS