Figure 1.

Pheromone and pheromone receptor structures in the B mating type locus of L. edodes. (A) Structures of the B4 and B12 mating types. The B mating type loci consist of distinct Bα and Bβ subloci which contain different pheromones (phbs) and receptor genes (rcbs). Arrow boxes indicate the direction of transcription. (B) Amino acid sequence of mature pheromones. (C) Amino acid sequence comparison of pheromone receptors. Loop regions are shown within boxes and the amino acids predicted to be located in transmembrane domains are colored in red. RCB1-2 and RCB1-4 represent pheromone receptors found in the Bα sublocus of B4 and B12 mating types, respectively, whereas RCB2-1 and RCB2-3 are the receptors found in the Bβ sublocus of B4 and B12, respectively.