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. Author manuscript; available in PMC: 2019 Nov 23.
Published in final edited form as: Annu Rev Genet. 2018 Sep 5;52:65–87. doi: 10.1146/annurev-genet-120417-031621

Fig 3. Cellular consequences of YAP activity.

Fig 3

As described in the text, YAP activity has diverse consequences for cells during normal development and physiology. It often increases tissue growth by promoting cellular growth and cell proliferation, and inhibiting apoptosis. It also helps to maintain stem and progenitor cells in many tissues, while suppressing differentiation, but in other contexts can influence cell fate decisions or modify cellular phenotypes.