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. Author manuscript; available in PMC: 2020 Jan 1.
Published in final edited form as: Semin Nephrol. 2019 Jan;39(1):107–116. doi: 10.1016/j.semnephrol.2018.10.009

Table.

Prebiotics and probiotics in kidney disease.

Strain Disease type Effect Year Reference

probiotics Lactobacillus. acidophilus CKD stage3,4 Decrease Bun, Cr, uric acid, uremic toxins 2009
2010
[78,79]

Diabetic + HD Glucose homeostasis, Inflammation, oxidative stress 2017 [80]

Aging mice Kidney klotho marker 2012 [81]

Lactobacillus. casei LPS induced acute inflammatory model Regulate immuno-coagulative response 2018 [82]

Lactobacillus. rhamnosus MRL/lpr lupus nephritis model Anti-inflammatory, decreased IgG2a in kidney, adjust immunity 2017 [83]

Bifidobacteria. bifidum Mice model of primary hyperoxaluria Limiting absorption across intestine 2015 [84]

prebiotics Oat and barley beta-glucans Healthy individuals Decrease p-cresyl sulfate 2017 [85]

xylooligosaccharide Obese rats Decrease renal oxidative stress and apoptosis 2018 [86]

Abbreviations: CKD: chronic kidney disease; Bun: blood urea nitrogen; Cr: creatinine; HD: hemodialysis; LPS: Lipopolysaccharide.