Table 2.
Demographic features and disease status at presentation
| All | MPO-ANCA | PR3-ANCA | P-value | |
|---|---|---|---|---|
| Demographics | ||||
| n (%) | 66 (100) | 33 (50) | 33 (50) | |
| Male:female, % | 58:42 | 52:48 | 64:36 | 0.46 |
| Age (years), median (range) | 62 (17–84) | 68 (17–84) | 59 (19–81) | 0.04 |
| Comorbidities, % | ||||
| Respiratory | 21 | 30 | 12 | 0.13 |
| Cardiac | 12 | 15 | 9 | 0.71 |
| Diabetes | 12 | 15 | 9 | 0.71 |
| Hypothyroidism | 18 | 18 | 18 | 1.00 |
| Disease status | ||||
| De novo presentation, % | 89 | 91 | 88 | |
| BVAS, median (range) | 18.5 (12–31) | 17 (12–31) | 21 (12–29) | <0.01 |
| Creatinine (μmol/L), median (range) | 205 (63–479) | 213 (74–479) | 180 (63–440) | 0.56 |
| eGFR (mL/min), median (range) | 25 (8–86) | 24 (8–71) | 33 (8–90) | 0.44 |
| Biopsy class, % | 0.65 | |||
| Focal | 24 | 21 | 27 | |
| Crescentic | 33 | 30 | 33 | |
| Mixed | 42 | 48 | 36 | |
| Tubular atrophy, % (range) | 10 (0–50) | 20 (10–50) | 10 (0–40) | 0.01 |