Table 4.
Author | Lee et al 200856 | Xu and Liu 201257 | Sun et al 201658 | The present meta-analysis |
---|---|---|---|---|
Number of RCTs | 5 | 5 | 11 | 15 |
Participants | Osteoporosis | Postmenopausal women | Perimenopausal and postmenopausal women | Osteopenia and primary osteoporosis |
Search strategy until (year) | 2007 | 2012 | 2015 | 2017 |
Protocol registered | NA | NA | NA | Applied |
Trial sequential analysis | NA | NA | NA | Applied |
Outcomes | BMD | BMD | BMD, bone turnover markers | BMD, BGP, serum calcium, serum phosphorus, VAS, CTX, OSC |
Abbreviations: BGP, bone gla protein; BMD, bone mineral density; CTX, C-terminal telo-peptide of type I collagen; NA, not available; OSC, osteocalcin; RCTs, randomized controlled trials; VAS, Visual Analog Scale.