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. 2019 Jan 3;14:91–104. doi: 10.2147/CIA.S187588

Table 4.

Comparison with other previous meta-analyses

Author Lee et al 200856 Xu and Liu 201257 Sun et al 201658 The present meta-analysis
Number of RCTs 5 5 11 15
Participants Osteoporosis Postmenopausal women Perimenopausal and postmenopausal women Osteopenia and primary osteoporosis
Search strategy until (year) 2007 2012 2015 2017
Protocol registered NA NA NA Applied
Trial sequential analysis NA NA NA Applied
Outcomes BMD BMD BMD, bone turnover markers BMD, BGP, serum calcium, serum phosphorus, VAS, CTX, OSC

Abbreviations: BGP, bone gla protein; BMD, bone mineral density; CTX, C-terminal telo-peptide of type I collagen; NA, not available; OSC, osteocalcin; RCTs, randomized controlled trials; VAS, Visual Analog Scale.