TABLE 2.
Diagnostic Testing and Treatment Within 48 Hours of Admission in Children With NI Hospitalized for Pneumonia
Characteristic | Overall Cohort (n = 27455) | Aspiration Pneumonia (n = 2659) | Nonaspiration Pneumonia (n = 24796) | P a | |||
---|---|---|---|---|---|---|---|
n | % | n | % | n | % | ||
Laboratory Testing | |||||||
Complete blood count | 19 262 | 70.2 | 2198 | 82.7 | 17 064 | 68.8 | <.001 |
Blood culture | 16 041 | 58.4 | 1779 | 66.9 | 14 262 | 57.5 | <.001 |
Chemistry profile | 11 967 | 43.6 | 1522 | 57.2 | 10 445 | 42.1 | <.001 |
Viral study | 10 481 | 38.2 | 1091 | 41.0 | 9390 | 37.9 | .001 |
C-reactive protein | 7277 | 26.5 | 780 | 29.3 | 6497 | 26.2 | .001 |
Blood gas | 7166 | 26.1 | 1220 | 45.9 | 5946 | 24.0 | <.001 |
Urine culture | 4136 | 15.1 | 732 | 27.5 | 3404 | 13.7 | <.001 |
Respiratory culture | 2157 | 7.9 | 414 | 15.6 | 1743 | 7.0 | <.001 |
Erythrocyte sedimentation rate | 1544 | 5.6 | 144 | 5.4 | 1400 | 5.6 | .620 |
Coagulation study | 1492 | 5.4 | 234 | 8.8 | 1258 | 5.1 | <.001 |
Liver function test | 645 | 2.3 | 126 | 4.7 | 519 | 2.1 | <.001 |
Radiographic imaging | |||||||
Chest radiograph | 23 793 | 86.7 | 2440 | 91.8 | 21 353 | 86.1 | <.001 |
Chest computed tomography | 650 | 2.4 | 33 | 1.2 | 617 | 2.5 | <.001 |
Chest ultrasound | 453 | 1.6 | 15 | 0.6 | 438 | 1.8 | <.001 |
Treatment | |||||||
Empirical antimicrobial coverage | <.001 | ||||||
Pneumococcal | 16 777 | 61.1 | 303 | 11.4 | 16 474 | 66.4 | |
Pneumococcal and anaerobic | 6107 | 22.2 | 1820 | 68.4 | 4287 | 17.3 | |
Other combinations | 2509 | 9.1 | 99 | 3.7 | 2410 | 9.7 | |
Pneumococcal, anaerobic, and antipseudomonal | 2062 | 7.5 | 437 | 16.4 | 1625 | 6.6 | |
Adjunct therapy | |||||||
Inhaled β agonist | 18 784 | 68.4 | 1830 | 68.8 | 16954 | 68.4 | .640 |
Inhaled corticosteroids | 7737 | 28.2 | 1182 | 44.5 | 6555 | 26.4 | <.001 |
Systemic steroids | 78 | 0.3 | 8 | 0.3 | 70 | 0.3 | .860 |
P value for χ2 test for categorical variables and for Wilcoxon rank sum test for continuous variables.