Table 2.

The effect of brainstem and/or subcortical infarct locations on impaired HRQOL at three month from the adjusted models (n = 229)

Predictors		Impaired HRQOLa			Disability by mRSb
		OR	95% CI	P	OR	95% CI	P
Subcortical and/or brainstem infarct location		2.54	1.29–5.01	<0.01	2.46	0.37–16.42	0.35
Any rehabilitation after hospital		4.21	2.15–8.21	<0.01	19.71	3.60–108.01	<0.01
Baseline mRS 2–3 vs. 0–1		1.14	0.40–3.23	0.81	1.03	0.21–5.01	0.97
Current smoking (<6 months)		0.62	0.26–1.49	0.29	0.44	0.08–2.53	0.36
Private insurance		0.31	0.15–0.64	<0.01	0.41	0.11—1.50	0.18
Initial NIHSS score (per point)		1.17	0.94–1.47	0.17	1.67	1.14–2.43	<0.01
Proxy follow-up reporting		2.53	0.84–7.59	0.10	8.87	2.42–32.56	<0.01
Volume Groups	Q2 (0.02–0.72 cc)	1.13	0.44–2.89	0.80	0.82	0.25–2.64	0.73
	Q3 (0.73–3.34 cc)	0.95	0.40–2.31	0.92	0.88	0.30–2.54	0.81
	Q4 (>3.35 cc)	1.26	0.50–3.17	0.63	0.84	0.28–2.55	0.76
	Ql (0.01 cc)	1.00			1.00

^aImpaired HRQOL is defined as 5 points below the population mean of 50 for any of the domain (i.e. T-score < 45). Bold values represent p-values ≤0.05.

^bDisability is defined by mRS ≥2.

HRQOL: health-related quality of life; mRS: modified Rankin Score; NIHSS: National Institutes of Health Stroke Scale; Q: quartile; MIS: mild ischemic stroke; cc: cubic centimeters.