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. Author manuscript; available in PMC: 2019 Oct 1.
Published in final edited form as: Cytoskeleton (Hoboken). 2018 Oct;75(10):450–457. doi: 10.1002/cm.21496

Figure 1: AMBMP is a potent inhibitor of microtubule growth.

Figure 1:

(a-b) Representative images of false colored CLIP170-GFP showing changes to MT growth after treatment with AMBMP (a, see Supplemental Movie 1) and quantification (b) of those changes as measured by the comet length of CLIP170-GFP in cells immediately after treatment with AMBMP at the labeled doses (n = 50–100 comets from 3 cells). (c-e) 10μM treatment with AMBMP results in a complete loss of MT growth (c and e, see Supplemental Movie 2) which recovers within 7 minutes of washout (d and e, n > 150 comets from 2 cells, see Supplemental Movie 4). *** represents a p value less than 0.0005.