TABLE 1.
List of 58 genes that are differentially regulated downstream of Sema6a/PlxnA2 signaling at 18 somites, common to both morphants compared to uninjected controls. GEO accession # GSE86246
| zfin symbol | ensembl gene ID | logFC Sema-UIC |
logFC Plexin-UIC |
|---|---|---|---|
| ace | ENSDARG00000079166 | 2.02 | 2.67 |
| ankrd50 | ENSDARG00000007077 | 1.59 | 1.99 |
| Atf5a | ENSDARG00000068096 | 2 | 2 |
| Atp1b4 | ENSDARG00000053262 | −1.44 | −1.4 |
| Atxn1b | ENSDARG00000060862 | 3.99 | 4.3 |
| Azin1a | ENSDARG00000052789 | 1.36 | 1.6 |
| baxa | ENSDARG00000020623 | 1.35 | 1 |
| bbc3 | ENSDARG00000069282 | 2.37 | 3.35 |
| caprin2 | ENSDARG00000020749 | 1.36 | 1.29 |
| casp8 | ENSDARG00000058325 | 3.55 | 3.5 |
| cd40 | ENSDARG00000054968 | 1.57 | 2.84 |
| Cdkn1a | ENSDARG00000076554 | 2.13 | 2.53 |
| cdkn2a | ENSDARG00000037262 | 3.05 | 3.28 |
| cica | ENSDARG00000071150 | 1.28 | 1.88 |
| Crygn1 | ENSDARG00000087437 | 2.31 | 2.27 |
| cxcr3.3 | ENSDARG00000070669 | 1.09 | 1.51 |
| dcdc2b | ENSDARG00000053744 | 1.25 | 2.16 |
| Dgki | ENSDARG00000063578 | 1.55 | 1.55 |
| exo5 | ENSDARG00000042727 | 3.22 | 3.48 |
| Fos | ENSDARG00000031683 | 3.05 | 2.81 |
| fosl1 | ENSDARG00000015355 | 2.4 | 2.03 |
| ftr85 | ENSDARG00000034707 | 1.5 | 2.09 |
| gadd45aa | ENSDARG00000043581 | 2.85 | 3.18 |
| gig2p | ENSDARG00000088260 | 1.23 | 1.32 |
| gpd1a | ENSDARG00000043701 | 1.64 | 1.74 |
| gpr61 | ENSDARG00000003900 | 1.85 | 2.2 |
| Gtpbp1l | ENSDARG00000042900 | 2.84 | 2.56 |
| igf2a | ENSDARG00000018643 | 1.51 | 1.82 |
| Inx1 | ENSDARG00000043323 | 1.4 | 1.41 |
| Lygl1 | ENSDARG00000056874 | 1.38 | 1.66 |
| mat2al | ENSDARG00000063665 | 2.89 | 2.64 |
| mdm2 | ENSDARG00000033443 | 1.76 | 1.91 |
| metrnl | ENSDARG00000007289 | 1.67 | 1.71 |
| mfap4 | ENSDARG00000090557 | 2.73 | 4.09 |
| mmp2 | ENSDARG00000017676 | 1.33 | 1.31 |
| ms4al7a.2 | ENSDARG00000093546 | 1.61 | 1.73 |
| nebl | ENSDARG00000021200 | 2 | 1.79 |
| nupr1 | ENSDARG00000094300 | 1.64 | 1.93 |
| parp3 | ENSDARG00000003961 | 1.96 | 1.77 |
| phlda2 | ENSDARG00000042874 | 1.28 | 1.63 |
| Pmaip1 | ENSDARG00000089307 | 2.15 | 1.89 |
| phlda3 | ENSDARG00000037804 | 3.64 | 3.57 |
| ppm1e | ENSDARG00000026499 | 1.06 | 1.1 |
| prox2 | ENSDARG00000041952 | 1.69 | 1.67 |
| rasl11b | ENSDARG00000015611 | 2.18 | 1.58 |
| rb12 | ENSDARG00000045636 | 3.52 | 3.68 |
| rd3 | ENSDARG00000031600 | 1.21 | 1.93 |
| rev1 | ENSDARG00000018296 | 1.6 | 1.41 |
| mf169 | ENSDARG00000042825 | 2.05 | 2.71 |
| rps27l | ENSDARG00000090186 | 2.06 | 2.08 |
| rpz5 | ENSDARG00000075718 | 3.37 | 3.37 |
| sesn1 | ENSDARG00000020693 | 1.49 | 2.57 |
| shtn1 | ENSDARG00000039697 | 1.21 | 1.12 |
| tnfaip6 | ENSDARG00000093440 | 1.33 | 1.19 |
| tnfrsf27 | ENSDARG00000079403 | 4.21 | 4.4 |
| tp53 | ENSDARG00000035559 | 1.23 | 1.37 |
| upb1 | ENSDARG00000011521 | 2.16 | 2.09 |