Table 4.

Multivariate Cox Proportional Hazard ratios (HR) and 95% Confidence Intervals (CI) for mortality at 2, 5, and 10 years

Variable	2 years		5 years		10 years
	HR	95% CI	HR	95% CI	HR	95% CI
Age
<60	Ref		Ref		Ref
≥60	1.47	1.16-1.86	1.52	1.27-1.81	1.57	1.34-1.85
Sex
Female	Ref		Ref		Ref
Male	1.15	0.98-1.34	1.17	1.04-1.32	1.18	1.06-1.31
Race
White	Ref		Ref		Ref
Black	1.22	0.96-1.56	1.14	0.94-1.38	1.13	0.94-1.34
Other	0.81	0.45-1.44	0.81	0.54-1.23	0.80	0.53-1.19
Histology
Fibrous	Ref		Ref		Ref
Lipomatous	0.49	0.38-0.64	0.55	0.46-0.66	0.59	0.50-0.70
Leiomyosarcoma	0.81	0.62-1.05	0.94	0.78-1.14	1.08	0.90-1.13
Synovial sarcoma	0.56	0.38-0.85	0.93	0.73-1.20	1.04	0.82-1.30
MPNST+	1.09	0.68-1.75	1.10	0.76-1.59	1.26	0.90-1.75
Grade
Low grade	Ref		Ref		Ref
High grade	6.38	4.59-8.89	3.17	2.63-3.81	2.61	2.23-3.06
Size
≤5 cm	Ref		Ref		Ref
5-10 cm	2.55	1.96-3.31	1.96	1.65-2.34	1.85	1.58-2.16
>10 cm	5.23	4.05-6.76	3.71	3.12-4.42	3.31	2.82-3.87
Site
Upper Extremity	Ref		Ref		Ref
Lower Extremity	1.08	0.87-1.33	1.05	0.90-1.22	1.06	0.91-1.22
SES*
8	Ref		Ref		Ref
6-7	1.03	0.83-1.28	1.06	0.90-1.24	1.11	0.96-1.28
4-5	1.21	0.97-1.50	1.17	0.99-1.37	1.18	1.02-1.37
<4	1.19	0.93-1.51	1.25	1.05-1.50	1.25	1.06-1.47
Insurance
Private insurance	Ref		Ref		Ref
Not insured	1.43	0.91-2.23	1.20	0.84-1.72	1.25	0.90-1.75
Medicaid	1.16	0.79-1.72	1.22	0.92-1.62	1.27	0.97-1.66
Medicare	1.54	1.22-1.94	1.49	1.26-1.77	1.57	1.34-1.84
Other government	1.19	0.59-2.42	1.34	0.80-2.24	1.34	0.81-2.20
Unknown	2.56	1.39-4.70	1.77	1.04-3.02	1.92	1.20-3.07
Margins
Negative	Ref		Ref		Ref
Positive	1.50	1.23-1.82	1.29	1.10-1.51	1.22	1.06-1.42
Radiation
No	Ref		Ref		Ref
External beam	0.57	0.49-0.67	0.69	0.61-0.78	0.73	0.65-0.82
Chemotherapy
No	Ref		Ref		Ref
Yes	0.91	0.75-1.11	0.98	0.84-1.13	0.94	0.81-1.07
Volume
High	Ref		Ref		Ref
Low	1.26	1.10-1.47	1.24	1.10-1.39	1.22	1.10-1.36

⁺MPNST – malignant peripheral nerve sheath tumor

^*SES = socioeconomic composite score