Regional GMV decrease in patients with acute EP compared with HCs. (A) Significantly decreased areas were observed in the left cerebellum posterior lobe, the left limbic lobe, the right insula, the left insula, the left thalamus, the left caudate, and the right cuneus. The blue areas indicate lower GMV brain regions. The significance level was set at P < 0.05, (GRF) theory corrected (z > 2.3). The mean GMV values between the EPs and HCs group (B).