Table 2. Laboratory characteristics among patients with DVI with and without AKI.
| Parameters | Overall | Non-AKI | AKI | P-value§ | |||
|---|---|---|---|---|---|---|---|
| N | Median (IQR) | N | Median (IQR) | N | Median (IQR) | ||
| WBC (×103/μL) | 1,484 | 3.3 (2.4–4.8) |
1,413 | 3.3 (2.4–4.7) |
71 | 4.5 (2.5–5.5) |
0.013 |
| Neutrophils (%) | 1,484 | 48.0 (34.0–63.0) |
1,413 | 48.0 (33.0–62.9) |
71 | 55.0 (43.0–64.0) |
0.009 |
| Lymphocytes (%) | 1,484 | 27.0 (19.0–37.0) |
1,413 | 28.0 (19.0–37.0) |
71 | 23.0 (14.0–30.0) |
0.001 |
| Atypical lymphocytes (%) | 1,484 | 10.0 (5.0–18.0) |
1,413 | 10.0 (5.0–18.0) |
71 | 9.0 (4.0–13.0) |
0.038 |
| RBC (×106/μL) | 1,484 | 5.07 (4.60––5.55) |
1,413 | 5.07 (4.61–5.54) |
71 | 4.99 (4.41–5.75) |
0.625 |
| Platelet (×103/μL) | 1,484 | 67 (37–104) |
1,413 | 68 (37–104) |
71 | 63 (35–88) |
0.141 |
| Hemoglobin (g/dL) | 1,484 | 13.9 (12.8–15.2) |
1,413 | 14.0 (12.9–15.2) |
71 | 13.8 (12.7–15.4) |
0.671 |
| Hematocrit (%) | 1,484 | 41.2 (38.3–44.7) |
1,413 | 41.3 (38.3–44.6) |
71 | 40.7 (37.3–45.1) |
0.648 |
| Serum creatinine (mg/dL)a | 1,484 | 0.80 (0.67–1.00) |
1,413 | 0.80 (0.65–0.98) |
71 | 1.23 (1.05–1.69) |
N/A |
| BUN (mg/dL) | 1,463 | 9.1 (6.9–11.9) |
1,392 | 8.9 (6.8–11.6) |
71 | 15.8 (11.1–18.8) |
N/A |
| Serum Na (mmol/L) | 1,387 | 136 (134–139) |
1,317 | 137 (134–139) | 70 | 135 (133–137) |
<0.001 |
| Serum K (mmol/L) | 1,387 | 3.7 (3.4–3.9) |
1,317 | 3.7 (3.4–3.9) |
70 | 3.9 (3.6–4.2) |
<0.001 |
| Serum HCO3 (mmol/L) | 1,387 | 24 (22–26) |
1,317 | 24 (23–26) |
70 | 23 (20–24) |
<0.001 |
| Serum albumin (g/L) | 1,069 | 4.1 (3.7–4.3) |
1,008 | 4.1 (3.7–4.3) |
61 | 4.1 (3.5–4.3) |
0.248 |
| Serum total bilirubin (mg/dL) | 1,051 | 0.4 (0.3–1.0) |
992 | 0.4 (0.3–0.6) |
59 | 0.6 (0.4–1.2) |
<0.001 |
| AST (IU/L) | 1,415 | 101 (57–213) |
1,348 | 99 (56–203) |
67 | 188 (88–929) |
<0.001 |
| ALT (IU/L) | 1,414 | 65 (33–142) |
1,347 | 65 (33–138) |
67 | 124 (46–406) |
<0.001 |
| PT (s) | 371 | 11.7 (11.0–12.6) |
329 | 11.6 (10.9–12.5) |
42 | 12.6 (11.8–15.5) |
<0.001 |
| INR | 371 | 1.02 (0.94–1.10) |
329 | 1.01 (0.93–1.09) |
42 | 1.11 (1.01–1.46) |
<0.001 |
| aPTT (s) | 363 | 31.2 (28.5–35.3) |
323 | 30.9 (28.3–34.2) |
40 | 35.5 (30.6–43.5) |
<0.001 |
| CPK (U/L) | 282 | 152 (82–296) |
250 | 144 (79–265) |
32 | 354 (173–762) |
<0.001 |
| Serum lactate (mg/dL) | 239 | 13.0 (10.7–16.8) |
205 | 12.8 (10.7–15.7) |
34 | 18.5 (11.3–111.0) |
<0.001 |
WBC: white blood cell; RBC: red blood cell; BUN: blood urea nitrogen; AST: aspartate aminotransferase; ALT: alanine aminotransferase; PT: prothrombin time; INR: international normalized ratio; aPTT: activated partial thromboplastin time; CPK: creatine phosphokinase
anormal reference range according to hospital values: 0.67–1.17 mg/dl for males and 0.51–0.95 mg/dl for females
§Mann–Whitney U test