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. Author manuscript; available in PMC: 2019 Jan 7.
Published in final edited form as: Ann Appl Stat. 2018 Nov 13;12(4):2457–2482. doi: 10.1214/18-AOAS1162

Fig. 4.

Fig. 4.

Spike detection for cell 2002 of the Chen et al. (2013) data. The observed fluorescence (Inline graphic) and true spikes (Inline graphic) are displayed. Estimated spike times from the0 problem (4) are shown in (Inline graphic), estimated spike times from the1 problem (3) are shown in (Inline graphic), and estimated spike times from the post-thresholding estimator (9) are shown in (Inline graphic). Times 0s–35s are shown in the top row; the second row zooms into time 30s–40s in order to illustrate the behavior around a large increase in calcium concentration.