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. Author manuscript; available in PMC: 2019 Jan 7.

Published in final edited form as: Ann Appl Stat. 2018 Nov 13;12(4):2457–2482. doi: 10.1214/18-AOAS1162

Fig. 5. — The first 10,000 timesteps from the second ROI in NWB 510221121 from the Allen Brain Observatory. Each panel displays the DF/F-transformed fluorescence (), the estimated spikes from the ℓ₀ problem () (5), the estimated spikes from the ℓ₁ problem () (3), and the estimated spikes from post-thresholding the ℓ₁ problem () (9). The panels display results from applying the ℓ₁ and ℓ₀ methods with tuning parameter λ chosen to yield (a): 27 spikes for each method; (b): 49 spikes for each method; and (c): 128 spikes for each method. The post-thresholding estimator was obtained by applying the ℓ₁ method with λ = 1, and thresholding the result to obtain 27, 49 or 128 spikes. (d)–(f): As in (a)–(c), but zoomed in on 200–250 seconds.

Inline graphic — The first 10,000 timesteps from the second ROI in NWB 510221121 from the Allen Brain Observatory. Each panel displays the DF/F-transformed fluorescence (), the estimated spikes from the ℓ₀ problem () (5), the estimated spikes from the ℓ₁ problem () (3), and the estimated spikes from post-thresholding the ℓ₁ problem () (9). The panels display results from applying the ℓ₁ and ℓ₀ methods with tuning parameter λ chosen to yield (a): 27 spikes for each method; (b): 49 spikes for each method; and (c): 128 spikes for each method. The post-thresholding estimator was obtained by applying the ℓ₁ method with λ = 1, and thresholding the result to obtain 27, 49 or 128 spikes. (d)–(f): As in (a)–(c), but zoomed in on 200–250 seconds.