Table 2.
Summary of Vmax, Km, kcat, and Ki
| Vmax | Km | kcat | Ki | n | |
|---|---|---|---|---|---|
| μm s−1 | μm | 104 s−1 | nm | ||
| acSPD | |||||
| No antibody | 391 ± 38 | 387 ± 74 | 39 ± 4 | NAa | 5 |
| aZ-mAb-1 | 184 ± 38b | 197 ± 64b | 18 ± 4 | NA | 3 |
| aZ-mAb-2 | 348 ± 22 | 489 ± 45 | 35 ± 2 | NA | 3 |
| aZ-mAb-3 | 152 ± 27b | 166 ± 36b | 15 ± 3 | NA | 3 |
| aZ-mAb-4 | 349 ± 61 | 347 ± 87 | 35 ± 6 | NA | 4 |
| aZ-mAb-5 | 339 ± 60 | 421 ± 102 | 34 ± 6 | NA | 3 |
| aZ-mAb-6 | 371 ± 35 | 857 ± 84b | 37 ± 4 | 21 ± 2 | 3 |
| aZ-mAb-7 | 365 ± 19 | 1172 ± 255b | 37 ± 2 | 9 ± 2 | 3 |
| aZ-mAb-9 | 281 ± 58b | 424 ± 109 | 28 ± 6 | NA | 3 |
| aZ-mAb-10 | 308 ± 42b | 451 ± 102 | 31 ± 4 | NA | 3 |
| zSPD | |||||
| No antibody | 295 ± 93 | 256 ± 54 | 0.77 ± 0.09 | NA | 10 |
| aZ-mAb-4 | 445 ± 14b | 193 ± 9 | 0.89 ± 0.03 | NA | 3 |
| aZ-mAB-6 | 260 ± 14 | 901 ± 39b | 0.52 ± 0.03 | NA | 3 |
| aZ-mAb-7 | 346 ± 8 | 609 ± 14b | 0.69 ± 0.02 | NA | 3 |
a NA, not applicable.
b Statistically significant difference from “no antibody” by unpaired t test calculated using GraphPad QuickCalcs online software.