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. Author manuscript; available in PMC: 2020 Jan 1.
Published in final edited form as: J Immunol Methods. 2018 Oct 31;464:64–73. doi: 10.1016/j.jim.2018.10.013

Fig. 3.

Fig. 3.

One-point neutralization assay of SIVsmE660.CR54 single mutants by various SIVmAbs. Percentage of neutralization was assessed at 10 μg/ml of SIVmAbs in eight replicates. (A) Neutralization by 1st generation SIVmAbs. (B) Neutralization by 2nd generation SIVmAbs. Statistical differences in percent neutralization against original SIVsmE660.CR54 were analyzed by Mann-Whitney U test. P-value: ** ≤ 0.01 < * ≤ 0.05. Mutations that increased sensitivities to NAb are shown in magenta and mutations that made virus more resistant to NAb are shown in blue.