. Author manuscript; available in PMC: 2019 Jan 7.

Published in final edited form as: Converg Sci Phys Oncol. 2018 Jan 3;4(1):015001. doi: 10.1088/2057-1739/aa9e6e

Table 2.

Bulk tumor-based theoretical estimates of diffusivity in the literature using an RD model.

Study	Modeling	D (μm² h⁻¹)
Anderson et al [3]	Generic tumor growth	3600
Jiang et al [42]	Generic tumor growth	3.6
Tracqui et al [40]	Anaplastic astrocytoma (estimated by CT)	43 000–46 000
Woodward et al [33]	Glioma	1800–5400
Burgess et al [43]	High grade glioma (Fisher’s approximation)	5400
	Low grade glioma (HG Glioma/10)	540
Swanson et al [32]	GBM gray matter (Fisher’s approximation)	5400
	GBM white matter (Fisher’s approximation)	27 000
Rockne et al [39]	Glioma (estimated by MRI)	600–37 000
Wang et al [20]	GBM (preoperative MRI)	34–36 000
Eikenberry et al [37]	Motile ‘go’ GBM cells (estimated by Stokes-Einstein relationship)	4200
	Non-motile ‘grow’ GBM cells	80
Harko et al [7]	GBM (estimated from Rockne 2009)	16 300
Hathout et al [44]	GBM	16 700