GM3 immunostaining in the amygdala and cortex of PPS treated MPS IIIA mice. Panels (a, b) show representative images from 32-week-old, sham injected MPS IIIA mice. Panels (c, d) show representative images from group 1 mice treated with PPS. Panels (e, f) show representative images from the amygdala of 16-week-old sham and ICV treated MPS IIIA mice, respectively