Fig. 9.

Semi-quantitative analysis of neuropathologic markers in PPS treated MPS IIIA mice. Semi-quantitative analysis of the staining intensities was determined in PPS and sham treated MPS IIIA mice as described in the Materials and Methods. Two blinded readers examined and scored at least three slides per mouse per group. The percent reduction in staining is shown in the PPS vs. the age-matched MPS IIIA control mice for subQ (group 1, panel a) and ICV (panel b) treated animals. The mean values are graphed from the six determinations (two readers and three slides each), and the vertical lines indicate the ranges