eTable 2. SOFA (Sequential Organ Failure Assessment) score as a basis for defining sepsis according to the ESCIM (European Society for Intensive Care Medicine) consensus.

			Points
Organ	Parameter		1	2	3	4
Lung	PaO2/FiO2	mmHg	<400	<300	<200 with respir. support	<100 with respir. support
Kidney	Creatinine or urinary output	mg/dL mL/day	1.2–1.9 –	2.0–3.4 –	3.5–4.9 <500	≥ 5.0 <200
Liver	Bilirubin	mg/dL	1.2–1.9	2.0–5.9	6.0–11.9	≥ 12.0
Cardiovascular system	Blood pressure and catecholamines	mmHg	Mean arterial pressure <70	Catechol. low*	Catechol. moderate*	Catechol. high*
Blood	Platelets	1000/mm3	<150	<100	<50	<20
CNS	Glasgow Coma Scale		14–13	12–10	9–6	<6

*Catecholamine dose

low = dopamine = 5 or dobutamine (each dose) for at least 1 hour

moderate = dopamine >5 or epinephrine/norepinephrine = 0.1 µg/kg per min

high = dopamine >15 or epinephrine/norepinephrine >0.1 µg/kg per min