Table 1.

Mean particle size, polydispersity index (PDI), and zeta potential of diclofenac chitosan loaded nanoparticles (DIC.CNPs).

Formula	Chitosan concentration (mg/ml)	Particle size (nm, mean ± SD)	PDI (Mean ± SD)	Zeta potential (mV, mean ± SD)	EE% (Mean ± SD)
LMW.DIC.CNPs	5 mg/ml	295.33 ± 3.01	0.185 ± 0.016	29.3 ± 1.80	29.3 ± 4.3
HMW.DIC.CNPs		336 ± 22.1	0.246 ± 0.07	22.53 ± 1.76	31.1 ± 3.1

Values are means ± standard deviation (SD) of at least three experiments (n = 3). EE%, percentage entrapment efficiency; LMW.DIC.CNPs, diclofenac-loaded low-molecular weight chitosan nanoparticles; HMW.DIC.CNPs, diclofenac-loaded high-molecular weight chitosan nanoparticles.