Fig. 4.
Scanning electron microscopy of Microsporum canis MCA 01 treated with sub-inhibitory concentration of 8-hydroxyquinoline derivatives 1–3 (1: clioquinol; 2: 8-hydroxy-5-quinolinesulfonic acid; 3: 8-hydroxy-7-iodo-5-quinolinesulfonic acid) and untreated cells. A. Untreated cells; A1 (Bar = 20 µm); A2 (Bar = 2 µm). B. Hyphal cells treated with clioquinol 1; B1 (Bar = 20 µm); B2 (Bar = 2 µm): white arrow indicates irregular and rough cell walls with grooves. C. Hyphal cells treated with derivative 2; C1 (Bar = 20 µm); C2 (Bar = 2 µm): white arrow indicates irregular and rough cell walls with grooves. D. Hyphal cells treated with derivative 3; D1 (Bar = 20 µm); D2 (Bar = 2 µm): white arrows indicate irregular and rough cell walls with grooves, pitting and tears.