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. 2018 Nov 5;19:65–74. doi: 10.1016/j.molmet.2018.10.011

Figure 3.

Figure 3

Male Fap−/−mice fed normal rodent chow exhibit normal body weight, glucose and lipid tolerance. Adult male Fap+/+ and −/− mice were provided with RC and subjected to weekly metabolic tests beginning at 24 weeks of age. A) Body weight. B) Body composition. C) Average 24-hour food intake. D) OGTT and AUC analysis. E) Plasma insulin during OGTT. F) Plasma glucagon during OGTT. G) IPGTT and AUC analysis. H) Plasma insulin during IPGTT. I) Plasma glucagon during IPGTT. J) ITT and AUC analysis. K) Fasting plasma insulin prior to ITT. L) Plasma glucagon during ITT. M) TG levels during LTT and AUC analysis. Data were analyzed using 2-way ANOVA or two-tailed t-test. *P < 0.05.