Table 1.
Selected demographic and HIV disease characteristics of the CHARTER and NNTC clinical research populations.
| CHARTER cross-sectional cohort | Active NNTC cohort | Longitudinal NNTC cohort | NNTC tissue bank cohort | |||||
|---|---|---|---|---|---|---|---|---|
| Demographics and HIV characteristics: | N | Percentage | N | Percentage | N | Percentage | N | Percentage |
| Gender | ||||||||
| Male | 1222 | 76.5% | 465 | 77% | 1979 | 82% | 754 | 81% |
| Female | 375 | 23.5% | 137 | 23% | 445 | 18% | 181 | 19% |
| Race/ethnicity* | ||||||||
| Black | 771 | 48.3% | 194 | 32% | 789 | 33% | 280 | 30% |
| White | 634 | 39.7% | 332 | 55% | 1356 | 56% | 556 | 59% |
| Hispanic (any race) | 151 | 9.5% | 177 | 30% | 655 | 27% | 253 | 27% |
| Other | 41 | 2.6% | 75 | 12% | 272 | 11% | 99 | 11% |
| Educational attainment | ||||||||
| Less than high school diploma/equivalency | 293 | 18.5% | 168 | 28% | 680 | 32% | 135 | 29% |
| High school diploma/equivalency | 399 | 25.2% | 114 | 19% | 486 | 23% | 126 | 27% |
| Some college/associate's degree | 622 | 39.2% | 183 | 31% | 596 | 28% | 134 | 28% |
| Bachelor degree | 169 | 10.6% | 80 | 13% | 240 | 11% | 38 | 8% |
| Graduate degree/graduate work | 102 | 6.4% | 54 | 9% | 155 | 7% | 40 | 8% |
| Current ARV medication use | 1122 | 70.8% | 556 | 92% | 1940 | 80% | 490 | 52% |
| HIV risk category | ||||||||
| IV drug use | 167 | 14.1% | 122 | 20% | 598 | 25% | 271 | 29% |
| Homosexual sexual contact | 608 | 51.2% | 285 | 47% | 1109 | 46% | 366 | 39% |
| Heterosexual sexual contact | 358 | 30.2% | 162 | 27% | 538 | 22% | 173 | 19% |
| Other | 54 | 4.5% | 33 | 5% | 182 | 7% | 125 | 13% |
| Demographics and HIV characteristics (cont.) | Value | Value | Value | Value | ||||
| Age | ||||||||
| 25th percentile | 38 | 42 | 38 | 41 | ||||
| Median | 43 | 51 | 44 | 48 | ||||
| 75th percentile | 49 | 61 | 52 | 56 | ||||
| CD4 count | ||||||||
| 25th percentile | 264 | 157 | 46 | 16 | ||||
| Median | 421 | 364 | 156.5 | 84 | ||||
| 75th percentile | 463 | 594 | 371 | 247 | ||||
| Log plasma viral load | ||||||||
| 25th percentile | Undetectable | 1.60 | 1.70 | 1.70 | ||||
| Median | 2.28 | 1.70 | 2.70 | 3.65 | ||||
| 75th percentile | 4.06 | 2.79 | 4.53 | 5.12 | ||||
The CHARTER cross-sectional study includes all CHARTER participants (those who did and did not recruit into a longitudinal substudy). The NNTC active cohort is currently enrolled and being followed on study. The longitudinal NNTC cohort includes both members of the active cohort and inactive participants. The NNTC tissue bank cohort includes all study participants who are deceased with autopsy. *The race/ethnicity data for the CHARTER study are collected in a single, mutually exclusive question; the data for NNTC are collected using separate race and ethnicity questions and are not mutually exclusive.